Multimodal Imaging in Inherited Retinal Disorders

From fundus photography to OCT and autofluorescence, modern imaging tools are transforming diagnosis, monitoring, and therapy guidance for IRDs.

By: Jin Kyun (Luke) Oh, MD, Jesse D. Sengillo, MD

Retinal Physician January 1, 2026 Vol 23, Issue January 2026 Page(s): 4-7

Clinical Report: Multimodal Imaging in Inherited Retinal Disorders

Overview

Expand to include additional imaging techniques such as near-infrared autofluorescence and fluorescein angiography.

Background

Inherited retinal disorders (IRDs) are a diverse group of degenerative diseases that affect photoreceptors and the retinal pigment epithelium, often presenting subtle early symptoms. The advancement of gene-based therapies necessitates accurate diagnosis and monitoring, making multimodal imaging increasingly important. These imaging modalities enhance the ability to identify biomarkers and track disease progression, which is crucial for patient management.

Data Highlights

Revise to state that while no numerical data is provided, qualitative insights are still valuable.

Key Findings

Cross-check findings with the source to ensure all points are accurately represented.

Clinical Implications

Clinicians should integrate multimodal imaging into their diagnostic and management protocols for IRDs to enhance patient outcomes. Understanding the specific roles of each imaging modality can aid in timely diagnosis and effective monitoring of disease progression.

Conclusion

The use of multimodal imaging is transforming the landscape of inherited retinal disorders, providing essential tools for diagnosis and management. Continued advancements in imaging technology will further improve patient care in this field.

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