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Article | 2026 Retina Society Meeting

Timing of Stage 2 ROP May Help Identify High-Risk Eyes

In a study presented at Retina Society, stage 2 diagnosis at an earlier postmenstrual age was associated with higher treatment rates and a greater proportion of zone I disease.

By: Jim Gallagher, senior managing editor
Retinal Physician September 26, 2026
5 Key Takeaways

  • 1

    Stage 2 retinopathy of prematurity (ROP) diagnosed at an earlier postmenstrual age (PMA) correlates with higher treatment rates.

  • 2

    The study reviewed 589 eyes from 311 infants diagnosed with stage 2 ROP across three neonatal intensive care units.

  • 3

    Treatment rates for stage 2 ROP varied significantly based on PMA at diagnosis, with 48.9% requiring treatment at 31 to <34 weeks.

  • 4

    A greater proportion of zone I disease was observed in eyes diagnosed with stage 2 ROP at earlier PMA.

  • 5

    The findings suggest that timing of diagnosis may need to be considered more in assessing high-risk infants for ROP.