5 Key Takeaways

• 1

  Aqueous chlorhexidine 0.05% significantly reduced conjunctival bacteria within 30 seconds before intravitreal injections.

• 2

  The study compared 30-second, 60-second, and 90-second exposure times to chlorhexidine, showing significant bacterial load reductions.

• 3

  Culture positivity decreased from 67.5% to 12.5% in the 30-second group, demonstrating effective antisepsis.

• 4

  Reductions in individual colony-forming units were similar across all exposure times, surpassing previous results with povidone-iodine.

• 5

  No adverse events were reported, supporting a standardized 30-second exposure protocol for chlorhexidine before IVI.