Features
Tips for Removing Foreign Bodies
Consider using the inferior port when removing IOFBs from the posterior segment.
By James C. Rice, FCOphth (SA), Jason Thomas, FCOphth (SA), Jonel Steffen, FCOphth (SA), et al.
A Roundtable on Complexities in Retinal Surgery
In Retinal Physician’s annual panel discussion, leading surgeons share challenging cases and evaluate their management.
By Christina Y. Weng, MD, MBA, John B. Miller, MD, Raymond Iezzi Jr, MD, et al.
In Research, Diversity Matters
Misleading assumptions reduce Black and Hispanic or Latino representation in clinical trials.
By Jeremiah Brown, MD, FASRS, Stephen Huddleston, MD, Kapil G. Kapoor, MD, FACS, FICS, FASRS
Robotic System Tested in Retinal Surgery
The first-in-human trial of the Luca system suggests robotic surgery may be safe and feasible.
By Jim Gallagher, senior managing editor
Scleral Buckling for Phakic Rhegmatogenous Retinal Detachment
Retinal surgeons are revisiting a time-tested technique in the modern era.
By Luis A. Acabá-Berrocal, MD, Maria H. Berrocal, MD
Web Exclusives
Bringing Retina Surgery Into the Office
A firsthand look at how a practice transitioned to office-based surgery for urgent and elective cases.
By Jonathan Feistmann, MD
Dietary Nutrients and Diabetic Retinopathy
A review of the protective effect of micronutrients for diabetic eye disease.
By Samuel Asanad, MD
Departments
Surgery, Science, and Inclusion
Upfront: This issue features articles on equitable research, complex surgical procedures, and treatment updates.
By Diana V. Do, MD
How Harrow Brought Triesence Back to Market
Retina Conversations: A conversation with Amir H. Shojaei, PharmD, PhD, Harrow’s chief scientific officer.
By Jim Gallagher, senior managing editor
An Update on Local Steroids for Uveitis
Uveitis Corner: As Retisert exits and Triesence returns, uveitis care enters a new phase.
By Sruthi Arepalli, MD
Navigating Retina Surgery Coding
Coding Q&A: Understand bundling rules and documentation requirements to ensure accurate billing.
By Elizabeth Cifers, MBA, MSW, CHC, CPC
Clinical Trial Update July/August 2025
Access Retinal Physician's listing of all active clinical trials in AMD, DME, RVO, and uveitis.
News
Systemic Complement Activation Linked to Progression of Intermediate AMD
“The classical pathway should receive more attention in the study of AMD pathogenesis,” the study researchers found.
By Sarah Fackler, managing editor, Optometric Management
Study Explores Cannabis Use and PVR Risk
Following retinal detachment repair, cannabis users demonstrated lower rates of postoperative prolierative vitreoretinopathy compared to controls.
By Sarah Fackler, managing editor, Optometric Management
Study Reveals Promising Drug Target in Uveal Melanoma
A landmark CRISPR–Cas9 screening study identified synthetic lethality between CDS1 and CDS2 for various tumor types.
By Sarah Fackler, managing editor, Optometric Management
ApoM Pathway May Offer New Target for Early AMD Intervention
A protein in the blood may help protect RPE cells by clearing out harmful fats.
Artificial Intelligence vs Lincoff for Retinal Detachment Diagnostics
What can AI learn from 1,000 retinal detachment cases? More than you’d think.
By Jim Gallagher, senior managing editor
Video: Faricimab Maintains Long-Term Stability in DME
Four-year data from the RHONE-X study, presented at ASRS, show sustained BCVA, CST improvements, and extended dosing potential in patients with diabetic macular edema.
By Veeral S. Sheth, MD, MBA, FACS
Video: No Evidence That AREDS Vitamins Slow GA Progression
A post hoc analysis of OAKS and DERBY data failed to support the foveal protection suggested by an earlier AREDS study.
By Paul Hahn, MD, PhD
Incoming ASRS President Shares Vision for Future
Geoffrey G. Emerson, MD, PhD, talks about inclusion, innovation, and why early career engagement is key to the Society’s continuing development.
By Jim Gallagher, senior managing editor
LIGHTSITE IIIB Extends PBM Evidence in Dry AMD
Findings from the multisite trial of photobiomodulation suggest visual gains can persist after reinitiation of therapy.
By Jim Gallagher, senior managing editor
Video: Tips for Treating Traction Retinal Detachments
Maria Berrocal, MD, shares her approach to these challenging cases with Diana Do, MD. The first day of the 2025 ASRS meeting focused on surgical technique and innovation.
Video: Surgical Retina Takes Center Stage at ASRS 2025
Gaurav Shah, MD, who planned the program for the annual meeting, explains why the first day was all about surgery.
Video: Should Fellow-Eye Lattice Prompt Early Laser?
Chase Ludwig, MD, joins Diana V. Do, MD, to review real-world data suggesting that prompt laser in lattice eyes may reduce future retinal detachments.
By Chase Ludwig, MD, Diana V. Do, MD
Video: Durable Results with Gore-Tex Sutures
Luis Acabá-Berrocal, MD, shares 8-year outcomes of Gore-Tex–sutured IOLs in complex eyes.
By Luis A. Acabá-Berrocal, MD
Study Finds Retinal Detachment Risk Elevated in ROP Adults
In adult patients with a history of retinopathy of prematurity, rates of retinal tear or detachment after cataract surgery far exceed those in the general population.
By Jim Gallagher, senior managing editor
Oral Gildeuretinol Slows Stargardt Progression
Interim data from TEASE‑3 presented at ASRS show stabilization of vision and retinal structure in patients with early-stage disease.
By Jim Gallagher, senior managing editor
Video: Dual-Action Gene Therapy for DME Shows Safety and Durability
David Almeida, MD, presented interim data from the SPECTRA trial of 4D-150 gene therapy in adults with diabetic macular edema
By DAVID R.P. ALMEIDA, MD, MBA, PHD
Video: Reducing Injections in Wet AMD
Avni Finn, MD, and Diana Do, MD, discuss promising results from the DAVIO2 trial of EYP-1901.
By Avni Finn, MD, MBA, Diana V. Do, MD
Aflibercept 8 mg Meets Primary Endpoint in QUASAR
Week 36 data reported at ASRS show sustained visual and anatomic improvement with fewer injections.
By Jim Gallagher, senior managing editor
New AI Model Predicts Course of Geographic Atrophy
A better understanding of GA lesion growth patterns could refine trial design and therapeutic decisions for late-stage dry AMD.
By Jim Gallagher, senior managing editor
Video: Getting Gas Tamponade Right
Gaurav Shah, MD, joins Diana Do, MD, to discuss how errors in intraocular gas concentration can lead to preventable blindness, and what surgeons can do to avoid vision-threatening mistakes.
By Gaurav K. Shah, MD, Diana V. Do, MD
Video: Study Confirms AI Accuracy in Home OCT Monitoring
Krishna Mukkamala, MD, presented a longitudinal analysis at ASRS showing that the home OCT algorithm closely matched expert grader assessments in near-daily scans of patients with neovascular AMD.
Higher-Volume Injections Don’t Elevate Glaucoma Risk
An analysis of real-world data finds no significant pressure increases or glaucoma risk with higher-volume agents aflibercept 8 mg, pegcetacoplan, or avacincaptad pegol.
By Jim Gallagher, senior managing editor
Complement Inhibition Slows GA in Eyes With Wet AMD
A retrospective analysis presented at ASRS 2025 shows a sharply reduced lesion growth rate and stable CNV activity in treated eyes.
By Jim Gallagher, senior managing editor
Video: Can a Glaucoma Drug Prevent Retinal Scarring?
Leo A. Kim, MD, PhD, shares early research with Diana Do, MD, on netarsudil’s emerging role in managing proliferative vitreoretinopathy.
By Leo A. Kim, MD, PhD, Diana V. Do, MD
Video: Long-Term GA Data Support Early Treatment
At ASRS 2025, Roger Goldberg, MD, presented 48-month results from OAKS, DERBY, and GALE. He discussed the findings with Diana Do, MD.
By Roger A. Goldberg, MD, MBA, Diana V. Do, MD
Video: Can Vonaprument Slow Vision Loss in GA?
David Eichenbaum, MD, and Diana Do, MD, discuss the rationale for and progress of the fully enrolled ARCHER II trial at ASRS 2025.
By David A. Eichenbaum, MD, Diana V. Do, MD
Port Delivery System Sustains nAMD Control Over 5 Years
Five-year data from the Portal extension study show durable outcomes with reduced treatment burden for Genentech’s Susvimo.
By Jim Gallagher, senior managing editor
OTX-TKI May Decrease Retinal Leakage in NPDR
A post hoc analysis of imaging from the HELIOS trial suggests a durable effect from the intraocular implant.
By Jim Gallagher, senior managing editor
Video: Fellow Eye Data Supports GA Clinical Trial Design
At ASRS, Diana Do, MD, presented results of a post hoc analysis of the OAKS and DERBY trials of geographic atrophy growth rates in untreated eyes vs sham eyes.
By Diana V. Do, MD, Roger A. Goldberg, MD, MBA
Study: Functional Testing Outperforms Structural Imaging in Predicting DR Progression
A prospective trial shows that ERG and pupillometry more accurately forecast progression to vision-threatening diabetic retinopathy.
Study: AI Delivers High Accuracy in IRD Diagnosis
A systematic review finds strongest performance for retinitis pigmentosa, with deep learning models achieving up to 99.9% accuracy across multiple imaging modalities.
By Sarah Fackler, managing editor, Optometric Management
Study Investigates DR in Native Americans
The CDC notes that while indigenous Americans face higher rates of diabetes, the prevalence of diabetic retinopathy in this population has received little study.
By Sarah Fackler, managing editor, Optometric Management
Supported Content
Peer Perspectives: Advances in Macular Telangiectasia Type 2 Care
Our experts discuss the treatment of MacTel and the importance of patient education.
By Sophie J. Bakri, MD, MBA, Roger A. Goldberg, MD, MBA
Phase 1b LOTUS Trial Targets IL-6R for DME
Novel pentavalent trispecific antibody addresses additional inflammatory pathway
By Veeral S. Sheth, MD, MBA, FACS, Michael A. Singer, MD
Peer Perspectives: Advances in Macular Telangiectasia Type 2 Care
Our experts examine patient selection for treatment and ongoing patient management.
By Sophie J. Bakri, MD, MBA, Roger A. Goldberg, MD, MBA
PER-001 Shows Functional and Structural Improvement in DR
"This is the first time we have seen a functional improvement in diabetic retinopathy," Dr. Khanani says.
By Arshad M. Khanani, MD, MA, FASRS, Michael A. Singer, MD