Understanding the Role of Bruch's Membrane in CNV
By:  Neda Barzegar-Befroei, MD; Tunde Peto, MD, PhD; Arthur A. Bergen, PhD; Imre Lengyel, PhD
The more we know about retinal structure, the better our chances of treating disease

Can Anti-VEGF Therapy Benefit Rare Retinal Diseases?
By:  Louis K. Chang, MD, PhD
Several case studies and series have offered some evidence for use

Visual Perception for the Blind: The BrainPort Vision Device
By:  Aimee Arnoldussen, PhD; Donald C. Fletcher, M.D.
By using their tongues, sightless people may be able to "see" again

Update on Clinical Genetic Testing for AMD
By:  Jaclyn L. Kovach, MD; Ingird U. Scott, MD, MPH
Several genetic screenings are now available to determine patients' risks

Can Nanotechnology Improve Treatment of Retinal Disease?
By:  Marco A. Zarbin, MD, PhD; Carlo Montemagno, PhD; James F. Leary, PhD; Robert Ritch, M.D.
Very small particles could mean very big changes for retina

Taking the EMR Plunge
By:  Michael Engelbert, MD, PhD
Live — and learn — vicariously as one retinal practice undertakes EMR implementation

The Pros & Cons of Conducting Clinical Trials in a Private Practice
By:  Michael D. Ober, MD
Opportunities to innovate are at hand, but not without hard work and risk

Wrapping up a Year in Retina
By:  Andrew E. Mathis, PhD, Medical Editor; Robert Murphy, Contributing Editor
A final sampling from our 2011 annual meeting offers guidance on imaging, surgical technique and the status of several investigational therapies

Special Section Sponsored By Alcon
By:  Maria H. Berrocal, MD
Direct PFO-Silicone Oil Exchange

Special Section Sponsored By Optos
By:  David S. Boyer, M.D.
Expanding Horizons in Retinal Imaging

Upfront: From the Editor-in-Chief
By:  Peter K. Kaiser, M.D.
Time to "think different" about EMR

Subspecialty News
Eylea maintains VA gains at 96 weeks; Rising Medicare costs for wet AMD; Microvascular changes predict disability; and more

Journal Club
New and noteworthy studies

Controversies in Care
By:  Michael Colucciello, MD
Fundus Autofluorescence Imaging: Illuminating Valuable Information?

Coding Q&A
By:  Riva Lee Asbell
Posterior Segment Intraocular Foreign Body Removal

Surgical Precision
By:  Steve Charles, MD, FACS, FICS
"Interface vitrectomy"

Clinical Trial Update

Focus On
By:  Samantha Stahl, Assistant Editor
Pattern laser offers homogenous success